Demographic and clinical data of the eight patients with rheumatoid arthritis from Leiden and the nine patients from Daw Park, who were studied for variations in cell infiltrate, and expression of matrix metalloproteinases and granzyme B of synovial tissue from cartilage-pannus junction and suprapatellar pouch
Patient | Age (years) | Sex (M/F) | Disease duration (months) | DMARDs1-150 | CRP1-150(mg/l) | RF1-150(+/−) | Erosions (+/−) |
1 | 54 | M | 30 | Plaquenil | 14 | − | + |
2 | 55 | M | 276 | — | 37 | − | − |
3 | 48 | F | 84 | MTX1-150 | 4 | − | + |
4 | 65 | M | 288 | MTX | 27 | + | + |
5 | 58 | F | 276 | MTX | 17 | − | + |
6 | 80 | F | 336 | Prednisone | 45 | + | + |
7 | 80 | F | 336 | Prednisone | 45 | + | + |
8 | 43 | F | 120 | MTX, prednisone, cyclosporin | 29 | + | + |
9 | 77 | M | 17 | Gold | 1 | − | − |
10 | 76 | F | 120 | Cyclosporin | 46 | + | + |
11 | 72 | F | 13 | — | 35 | + | + |
12 | 60 | F | 24 | Plaquenil | 80 | − | − |
13 | 77 | M | 180 | Gold | 16 | + | + |
14 | 70 | M | 1 | Gold, MTX | 116 | + | − |
15 | 75 | F | 3 | Gold | 47 | + | − |
16 | 76 | F | 1 | Gold | 32 | − | − |
17 | 59 | F | 216 | MTX | 108 | + | + |
↵1-150 DMARDs = disease modifying antirheumatic drugs; CRP = C reactive protein; RF = rheumatoid factor, MTX = methotrexate.