Mean semiquantitative scores for the expression of CD3+, CD4+, and CD8+ T cells, CD22+ B cells, CD38+ plasma cells, CD68+ macrophages, CD55+ fibroblast-like synoviocytes, and the expression of mast cells, matrix metalloproteinases MMP-1, MMP-3, MMP-13, and granzyme B7 in synovial tissue derived from cartilage-pannus junction (CPJ) and suprapatellar pouch (non-CPJ) from patients with rheumatoid arthritis. The data are shown as means (SD)
n | CPJ | Non-CPJ | |
CD3 (aggregates) | 17 | 1.5 (0.7) | 1.5 (0.8) |
CD3 (diffuse) | 17 | 2.9 (1.0) | 2.7 (1.0) |
CD4 | 17 | 2.5 (0.9) | 2.2 (1.0) |
CD8 | 16 | 2.3 (0.8) | 2.3 (1.1) |
CD22 | 17 | 2.3 (0.9) | 1.9 (0.7) |
CD38 | 17 | 2.5 (1.3) | 2.3 (1.3) |
CD68 (lining) | 16 | 2.1 (0.7) | 1.9 (1.1) |
CD68 (sublining) | 16 | 3.1 (0.9) | 2.8 (0.8) |
CD55 | 17 | 1.7 (0.7) | 1.4 (0.5) |
Mast cells | 16 | 1.9 (0.8) | 1.9 (0.9) |
MMP-1 | 15 | 1.7 (1.0) | 1.8 (1.3) |
MMP-3 | 15 | 2.6 (1.4) | 2.3 (1.4) |
MMP-13 | 15 | 2.5 (0.5) | 2.5 (1.0) |
Granzyme B7 | 15 | 1.3 (1.0) | 1.5 (1.3) |