Mean counts of CD3+, CD4+, and CD8+ T cells, CD22+ B cells, CD38+ plasma cells, CD68+ macrophages, and the integrated optical density (IOD) of matrix metalloproteinase-1 (MMP-1) and granzyme B7 in synovial tissue derived from cartilage-pannus junction (CPJ) and suprapatellar pouch (non-CPJ) from patients with rheumatoid arthritis, and measured by computer assisted digital image analysing. Results are shown as means (SEM)
n | CPJ | Non-CPJ | |
CD3 (count) | 17 | 1 228 (208) | 1 278 (245) |
CD4 (count) | 17 | 441 (91) | 437 (85) |
CD8 (count) | 16 | 144 (47) | 260 (143) |
CD22 (count) | 17 | 202 (41) | 127 (25) |
CD38 (count) | 17 | 1 411 (260) | 1 173 (231) |
CD68 sublining (count) | 16 | 2 968 (209) | 2 654 (249) |
Granzyme B (IOD) | 15 | 644 (136) | 703 (131) |
MMP-1 (IOD) | 15 | 71 749 (11 356) | 63 850 (9 280) |