Changes in symptoms and knee cartilage volume between baseline and 2 years later
| Baseline (n = 117) | Follow up (n = 117) | Mean change from baseline (95% CI) | |
|---|---|---|---|
| *WOMAC pain, stiffness, and function subscales (higher score indicates worse symptoms); †SF-36 components, standardised to Australian normal values (lower score indicates worse function). | |||
| Pain, mean (range)* | 81 (13–205) | 66 (0–210) | −17 (−26 to −8) |
| Stiffness, mean (range)* | 40 (0–96) | 31 (0–82) | −10 (−14 to −6) |
| Function, mean (range)* | 307 (42–711) | 247 (0–681) | −64 (−96 to −32) |
| Physical function, mean (range)† | 39 (16–58) | 38 (13–58) | −0.24 (−1.7 to 1.2) |
| Mental function, mean (range)† | 53 (25–67) | 52 (26–68) | 0.39 (−2.2 to 1.4) |
| Mean tibial cartilage volume (μm3), mean (range) | 3660 (1980–6610) | 3270 (1840–5610) | −390 (−460 to −330) |