Cause of death in patients with baseline RA-ILD
| DMARD cohort (n=14) | Anti-TNF cohort (n=70)* | |
|---|---|---|
| RA-ILD on death certificate | ||
| ILD as immediate cause of death | 1 (7) | 15 (22) |
| ILD present on death certificate | 2 (14) | 24 (35) |
| Underlying cause of death by ICD-10 chapter | ||
| Certain infectious and parasitic diseases | – | 3 (4) |
| Neoplasms | 5 (36) | 9 (13) |
| Diseases of the blood and blood-forming organs | – | 1 (1) |
| Endocrine, nutritional and metabolic diseases | – | 1 (1) |
| Circulatory | 4 (29) | 13 (19) |
| Respiratory | 3 (21) | 20 (29) |
| Digestive | – | 2 (3) |
| Musculoskeletal and connective tissue | 2 (14) | 17 (24) |
| Genitourinary | – | 2 (3) |
| External causes | – | 1 (1) |
| Missing | – | 1 (1) |
Figures represent number (%) of deaths.
↵* One missing cause of death in anti-TNF cohort. Percentages represent proportion of 69 patients with a reported cause of death.
DMARD, disease-modifying antirheumatic drug; ILD, interstitial lung disease; RA-ILD, rheumatoid arthritis-associated ILD; TNF, tumour necrosis factor.