Table 1

Power calculations for the JIA study

SNP	Locus	Allele frequency	Effect size (OR)	Power of JIA study (%)^*
rs10910099^†,^‡	MMEL	0.66	0.9	53
rs11889341^§	STAT4	0.22	1.12	48
rs7574865^§	STAT4	0.22	1.17	76
rs8179673^§	STAT4	0.22	1.13	55
rs10181656^§	STAT4	0.22	1.13	55
rs13207033^¶	TNFAIP3	0.79	0.86	67
rs6920220^‡	TNFAIP3	0.22	1.22	93
rs42041^**	CDK6	0.24	1.15	69
rs3761847^§	TRAF1	0.43	1.11	55
rs10818488^§	TRAF1	0.43	1.12	62
rs2900180^§	TRAF1	0.35	1.17	86
rs2812378^**	CCL21	0.34	1.12	59
rs4750316^‡	PRKCQ	0.80	0.85	72
rs1678542^‡	KIF5A	0.63	0.88	69
rs4810485^**	CD40	0.75	0.84	84

Sample size, 1054 JIA cases and 3531 controls.
↵* At α value 0.05, assuming a log-additive model;
↵† SNP in r²=0.95 with the SNP associated with RA in the WTCCC study;
↵‡ Barton et al (2008)19;
↵§ Barton et al (2008)14;
↵** Raychaudhuri et al (2008)20;
↵¶ Orozco et al (2009) (submitted).
JIA, juvenile idiopathic arthritis; OR, odds ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism.