Results for symptom outcomes: intent to treat analysis (N=125/126/123 for nominated VAS, KOOS pain, and KOOS ADL subscales, respectively)
| Variable | No brace | Brace | Between groups difference | |
|---|---|---|---|---|
| Mean at follow-up, when controlling for baseline value (95% CI) | Mean at follow-up, when controlling for baseline value (95% CI) | Brace/no brace difference (95% CI) | p Value | |
| Primary outcome: nominated VAS (0–10 cm) | 6.3 (5.9 to 6.8) | 5.0 (4.5 to 5.5) | −1.3 (−2.0 to −0.7) | <0.001 |
| KOOS pain subscale (100–0)* | 51.8 (48.6 to 54.9) | 57.5 (53.5 to 61.5) | 5.7 (0.6 to 10.8) | 0.03 |
| KOOS ADL subscale (100–0)* | 56.3 (53.4 to 59.2) | 60.8 (58.0 to 63.6) | 4.5 (0.5 to 8.5) | 0.03 |
*Increase in KOOS score represents improvement.
ADL, activities of daily living; KOOS, Knee Osteoarthritis Outcome Score; VAS, visual analogue scale.