Animal models

AB1111 GLYCOSYLATION OF γδT CELLS AS AN ESSENTIAL PLAYER IN THE IMMUNOPATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
B. Santos-Pereira, I. Alves, A. Campar, A. Marinho, C. Vasconcelos, S. Pinho

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1886; DOI: 10.1136/annrheumdis-2024-eular.1419
AB1115 VITAMIN D SUPPLEMENTATION PRESENTS A POSITIVE EFFECT ON MEMORY BUT NO EFFECT ON ANXIOUS-DEPRESSIVE BEHAVIOR IN A PRISTANE-INDUCED LUPUS MOUSE MODEL
T. E. Karnopp, G. Flores Chapacais, M. L. Gasparini, N. Garcia Dos Santos, V. Da Silva Freitas, M. Piccoli, A. Leite DI Domenico, L. Denardi Dória, N. M. Pereira de Souza, E. Correa Freitas, A. Rieger, O. A. Monticielo

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1888-1889; DOI: 10.1136/annrheumdis-2024-eular.2564
AB1119 REPRESSION OF ID3 AGGRAVATES LUPUS PHENOTYPES IN MURINE MODELS VIA ABERRANT B CELL DIFFERENTIATION
Y. Park, D. S. Kim, M. L. Cho, S. K. Kwok

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1891; DOI: 10.1136/annrheumdis-2024-eular.3801
AB1126 REBAMIPIDE ATTENUATES RENAL MANIFESTATIONS VIA ANTIOXIDANT EFFECTS ON PODOCYTES IN AN ANIMAL MODEL FOR SYSTEMIC LUPUS ERYTHEMATOSUS
Y. Park, Y. S. Song, D. S. Kim, S. G. Jang, S. K. Kwok

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1895; DOI: 10.1136/annrheumdis-2024-eular.3819
AB1141 THERAPEUTIC POTENTIAL OF INHIBITION OF JAK1 AND 2 BY RUXOLITINIB, OF ROCK2 BY BELUMOSUDIL, AND OF BTK BY IBRUTINIB IN SYSTEMIC SCLEROSIS
X. Hong, Y. Xiao, A. H. Györfi, L. Xu, L. Shen, R. Neelagar, V. Devakumar, T. Filla, T. Trinh-Minh, M. Liang, A. Rius Rigau, J. Distler, A. E. Matei

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1903; DOI: 10.1136/annrheumdis-2024-eular.5285
AB1153 IDENTIFYING THE INVOLVEMENT OF ADROPIN/ENHO IN SYSTEMIC SCLEROSIS (SSc) THROUGH MACHINE LEARNING AND MULTI-MODEL VALIDATION
J. Distler, M. Liang

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1909-1910; DOI: 10.1136/annrheumdis-2024-eular.1034
AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS
A. Young, S. Hernandez, E. Volkmann, H. Christofk

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1913; DOI: 10.1136/annrheumdis-2024-eular.439
AB1162 A SELECTIVE AND ORALLY BIOAVAILABLE CXCR7 MODULATOR’S IMPACT ON BLEOMYCIN-INDUCED SKIN FIBROSIS IN A MOUSE MODEL
Y. Kim, Y. Lee, E. Chae

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1914-1915; DOI: 10.1136/annrheumdis-2024-eular.2438
AB1164 ACCUMULATION OF MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES IN SYSTEMIC SCLEROSIS
A. Manfredi, N. Maugeri, G. A. Ramirez, A. Capobianco, A. Monno, F. Iannone, S. Franchini

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1915-1916; DOI: 10.1136/annrheumdis-2024-eular.2813
AB1166 EXTENDED RELEASE OF INHALED ILOPROST LIPOSOME (L608) FOR TREATMENT OF SYSTEMIC SCLEROSIS-RELATED RAYNAUD PHENOMENA AND DIGITAL ULCER
K. C. Chen, P. Kan, H. F. Liang

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1916; DOI: 10.1136/annrheumdis-2024-eular.5145

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