innate immunity

AB1103 GENERAL CLINICAL CHARACTERISTICS AND DAMAGE ACCRUAL IN PATIENTS WITH PROMINENT SYSTEMIC INFLAMMATORY FEATURES: PRELIMINARY DATA FROM A MONOCENTRIC LUPUS COHORT
G. Benanti, G. A. Ramirez, C. Vitellaro, C. Calabrese, S. Nannipieri, L. Moroni, E. Bozzolo, M. Matucci-Cerinic, L. Dagna

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1880-1881; DOI: 10.1136/annrheumdis-2024-eular.4980
AB1107 TYPE I INTERFERON ASSOCIATED GENE:GENE INTERRELATIONS MAY CONTRIBUTE TO EARLY DISEASE-ONSET AND HIGH DISEASE ACTIVITY IN JUVENILE-ONSET LUPUS
A. Charras, Y. Renaudineau, V. Natoli, M. Fusaro, E. MD Smith, M. W. Beresford, C. Hedrich, on behalf of UK jSLE Cohort Study

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1883; DOI: 10.1136/annrheumdis-2024-eular.3812
AB1111 GLYCOSYLATION OF γδT CELLS AS AN ESSENTIAL PLAYER IN THE IMMUNOPATHOGENESIS OF SYSTEMIC LUPUS ERYTHEMATOSUS
B. Santos-Pereira, I. Alves, A. Campar, A. Marinho, C. Vasconcelos, S. Pinho

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1886; DOI: 10.1136/annrheumdis-2024-eular.1419
AB1118 HUMAN CD141+ DENDRITIC CELLS (DCs) REPRESENT A UNIQUE TOLEROGENIC DC SUBSET THAT INDUCE IMMUNE-TOLERANCE IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS
X. Yuan, L. Sun, X. Qin, Y. Wang, Y. Chen, S. Liu, D. Wang

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1890-1891; DOI: 10.1136/annrheumdis-2024-eular.3359
AB1120 FCΓRIIB POLYMORPHISM IN SLE: ASSOCIATION WITH CLINICAL PHENOTYPES, DISEASE ACTIVITY AND LEVELS OF CYTOKINES (IL-6, IL-17 AND TNF-α)
B. K. Das, M. Tammana, S. Sahoo, S. Padhi, A. K. Panda, R. Tripathy, M. K. Parida, S. R. Tripathy, S. S. Pattanaik

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1891-1892; DOI: 10.1136/annrheumdis-2024-eular.5222
AB1128 SINGLE-CELL RNA SEQUENCING REVEALS CROSS-DISEASE CHARACTERIZATIONS OF TREATMENT-NAÏVE AUTOIMMUNE DISEASES AND DISTINCT INTERFERON SIGNATURES IN SYSTEMIC LUPUS ERYTHEMATOSUS
Z. Zhang, Y. Fan, Y. Geng, X. Ye, J. Zhao, H. Huang, J. Zhang

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1896; DOI: 10.1136/annrheumdis-2024-eular.4656
AB1130 A MICROSCOPY-BASED ASSAY TO MONITOR THE SLC15A4/TASL/IRF5 ACTIVATION STATUS IN RHEUMATIC DISEASES
L. Heinz, F. Kartnig, D. Sieghart, D. Mrak, D. Aletaha

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1897; DOI: 10.1136/annrheumdis-2024-eular.5725
AB1133 ASSESSMENT OF RELATIVE IMMUNE CELL POPULATIONS PRESENT IN TUBULOINTERSTITIAL AND GLOMERULAR TISSUE OF PATIENTS WITH LUPUS NEPHRITIS
R. Martinez-Canales, M. Montelongo Rojas, S. E. Rojas Gutierrez, C. Elizondo Solis, N. Macias-Segura, M. Salinas Carmona

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1898-1899; DOI: 10.1136/annrheumdis-2024-eular.980
AB1149 MONOCYTES DRIVE MYOFIBROBLAST CONTRACTION IN A 3D SKIN MODEL USED TO UNDERSTAND FIBROSIS IN SYSTEMIC SCLEROSIS
D. C. Zanin-Silva, N. Van Kooten, T. I. Papadimitriou, D. Dorst, B. Walgreen, E. Vitters, P. Van der Kraan, M. Van den Bosch, A. Van Caam, M. Koenders, on behalf of Reuma Lab

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1907-1908; DOI: 10.1136/annrheumdis-2024-eular.4834
AB1150 TYPE I INTERFERON ACTIVATION OF MONOCYTES IN SYSTEMIC SCLEROSIS IS CGAS-STING DEPENDENT AND CAN BE DIRECTLY INDUCED BY DERMAL FIBROBALSTS: A PROMISING THERAPEUTIC TARGET
S. Di Donato, R. Ross, C. W. Wasson, J. Schmitz, J. Li, S. Visvanathan, F. Del Galdo

Annals of the Rheumatic Diseases Jun 2024, 83 (Suppl 1) 1908; DOI: 10.1136/annrheumdis-2024-eular.4986

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