Methotrexate

Association of methotrexate polyglutamates concentration with methotrexate efficacy and safety in patients with rheumatoid arthritis treated with predefined dose: results from the MIRACLE trial
Hiroya Tamai, Kei Ikeda, Toshiaki Miyamoto, Hiroaki Taguchi, Chang-Fu Kuo, Kichul Shin, Shintaro Hirata, Yutaka Okano, Shinji Sato, Hidekata Yasuoka, Masataka Kuwana, Tomonori Ishii, Hideto Kameda, Toshihisa Kojima, Yurie Nishi, Masahiko Mori, Hideaki Miyagishi, Genta Toshima, Yasunori Sato, Wen-Chan Tsai, Tsutomu Takeuchi, Yuko Kaneko

Annals of the Rheumatic Diseases Oct 2024, ard-2024-226350; DOI: 10.1136/ard-2024-226350
Is a 1-year course of methotrexate in patients with arthralgia at-risk for rheumatoid arthritis cost-effective? A cost-effectiveness analysis of the randomised, placebo-controlled TREAT EARLIER trial
Elise van Mulligen, Sterre S Bour, Lucas M A Goossens, Pascal Hendrik Pieter de Jong, Maureen Rutten-van Mölken, Annette van der Helm-van Mil

Annals of the Rheumatic Diseases Sep 2024, ard-2024-226286; DOI: 10.1136/ard-2024-226286
An ulcerating skin tumour in a patient with rheumatoid arthritis
Laura C M Schenning, Rosanne Ottevanger, Koen D Quint, Sander W Tas

Annals of the Rheumatic Diseases Aug 2024, 83 (8) 1092; DOI: 10.1136/ard-2023-225436
Greetings from the editor 2024/2
Josef S Smolen

Annals of the Rheumatic Diseases Jun 2024, 83 (6) 685-686; DOI: 10.1136/ard-2024-226019
Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome
Katriona Goldmann, Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Nisha Nair, Cankut Cubuk, The MATURA Consortium, Paul McKeigue, Michael R Barnes, Anne Barton, Costantino Pitzalis, Myles J Lewis

Annals of the Rheumatic Diseases Mar 2024, 83 (3) 288-299; DOI: 10.1136/ard-2023-224540
HLA-DRB1 and HLA-DQA1 associated with immunogenicity to adalimumab therapy in patients with rheumatoid arthritis
Chuan Fu Yap, Nisha Nair, Annick de Vries, Floris C Loeff, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Anne Barton, Darren Plant

Annals of the Rheumatic Diseases Feb 2024, 83 (2) 263-265; DOI: 10.1136/ard-2023-223955
Disease activity drives transcriptomic heterogeneity in early untreated rheumatoid synovitis
Clément Triaille, Gaëlle Tilman, Tatiana Sokolova, Axelle Loriot, Joelle Marchandise, Stéphanie De Montjoye, Adrien Nzeusseu-Toukap, Laurent Méric de Bellefon, Caroline Bouzin, Christine Galant, Patrick Durez, Bernard R Lauwerys, Nisha Limaye

Annals of the Rheumatic Diseases Dec 2023, 82 (12) 1538-1546; DOI: 10.1136/ard-2023-224068
Clinical benefit of 1-year certolizumab pegol (CZP) add-on therapy to methotrexate treatment in patients with early rheumatoid arthritis was observed following CZP discontinuation: 2-year results of the C-OPERA study, a phase III randomised trial
Tatsuya Atsumi, Yoshiya Tanaka, Kazuhiko Yamamoto, Tsutomu Takeuchi, Hisashi Yamanaka, Naoki Ishiguro, Katsumi Eguchi, Akira Watanabe, Hideki Origasa, Shinsuke Yasuda, Yuji Yamanishi, Yasuhiko Kita, Tsukasa Matsubara, Masahiro Iwamoto, Toshiharu Shoji, Osamu Togo, Toshiyuki Okada, Désirée van der Heijde, Nobuyuki Miyasaka, Takao Koike

Annals of the Rheumatic Diseases Aug 2017, 76 (8) 1348-1356; DOI: 10.1136/annrheumdis-2016-210246
Safety and efficacy of the miR-124 upregulator ABX464 (obefazimod, 50 and 100 mg per day) in patients with active rheumatoid arthritis and inadequate response to methotrexate and/or anti-TNFα therapy: a placebo-controlled phase II study
Claire Daien, Marek Krogulec, Paul Gineste, Jean-Marc Steens, Laurence Desroys du Roure, Sophie Biguenet, Didier Scherrer, Julien Santo, Hartmut Ehrlich, Patrick Durez

Annals of the Rheumatic Diseases Aug 2022, 81 (8) 1076-1084; DOI: 10.1136/annrheumdis-2022-222228
Pausing methotrexate improves immunogenicity of COVID-19 vaccination in elderly patients with rheumatic diseases
Amanthi Nadira Arumahandi de Silva, Leonie Maria Frommert, Fredrik N Albach, Jens Klotsche, Veronika Scholz, Lara Maria Jeworowski, Tatjana Schwarz, Alexander ten Hagen, Jan Zernicke, Victor Max Corman, Christian Drosten, Gerd-Rüdiger Burmester, Robert Biesen

Annals of the Rheumatic Diseases Jun 2022, 81 (6) 881-888; DOI: 10.1136/annrheumdis-2021-221876

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