Sjögren’s syndrome (SS) is a chronic autoimmune disease characterised by dry eyes, dry mouth and focal lymphocytic infiltration in lacrimal and salivary glands. The infiltrating lymphocytes are mainly CD4 α/β T cells,¹ especially T helper 1 (Th1) type T cells, because they produce both interferon (IFN)γ and interleukin 2.^2,3 To understand the pathogenesis of SS, several molecules in labial salivary glands (LSGs) have been screened by microarray analysis in human SS. Hjelmervik et al⁴ and Gottenberg et al⁵ reported that the upregulated genes in SS salivary glands were IFN-inducible genes, such as IFN-stimulated transcription factor 3, IFN-regulatory factor 1 and B cell-activation factor of the TNF family. …