Ivarmacitinib, a selective Janus kinase 1 inhibitor, in patients with moderate-to-severe active rheumatoid arthritis and inadequate response to conventional synthetic DMARDs: results from a phase III randomised clinical trial

Jinjing Liu; Ying Jiang; Shangzhu Zhang; Shengyun Liu; Jingbo Su; Changsong Lin; Xiaohong He; Rui Wu; Lei Yang; Huaxiang Liu; Xinwang Duan; Shengqian Xu; Hui Luo; Jing Liu; Qibing Xie; Cundong Mi; Lin Chen; Ning Zhang; Huiping Gong; Jing Zhu; Yasong Li; Hua Wei; Long Qian; Jian Wang; Xiaofei Shi; Hongtao Jin; Zhenyu Jiang; Xi Xie; Feng Zhan; Xiuqin Geng; Zhaohui Zheng; Zhengfu Du; Guangchao Dong; Yuqi Sun; Xiaofeng Zeng

doi:10.1136/ard-2024-226385

Article info

Rheumatoid arthritis

Ivarmacitinib, a selective Janus kinase 1 inhibitor, in patients with moderate-to-severe active rheumatoid arthritis and inadequate response to conventional synthetic DMARDs: results from a phase III randomised clinical trial

Authors

Jinjing Liu Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China PubMed articles Google scholar articles
Ying Jiang Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China PubMed articles Google scholar articles
Shangzhu Zhang Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China PubMed articles Google scholar articles
Shengyun Liu Department of Rheumatology & Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China PubMed articles Google scholar articles
Jingbo Su Department of Rheumatology & Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China PubMed articles Google scholar articles
Changsong Lin Department of Rheumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China PubMed articles Google scholar articles
Xiaohong He Department of Rheumatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, China PubMed articles Google scholar articles
Rui Wu Department of Rheumatology and Immunology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China PubMed articles Google scholar articles
Lei Yang Department of Rheumatology and Immunology, Zhengzhou Central Hospital, Zhengzhou, China PubMed articles Google scholar articles
Huaxiang Liu Rheumatology Department, Qilu Hospital of Shandong University, Jinan, China PubMed articles Google scholar articles
Xinwang Duan Rheumatology and Immunology, The Second Affiliated Hospital of Nanchang University, Nanchang, China PubMed articles Google scholar articles
Shengqian Xu Rheumatology and Immunology Department, The First Affiliated Hospital of Anhui Medical University, Hefei, China PubMed articles Google scholar articles
Hui Luo Department of Rheumatology and Immunology, Xiangya Hospital, Central South University, Changsha, China PubMed articles Google scholar articles
Jing Liu Department of Rheumatology and Immunology Research Institute, Affiliated Hospital of North Sichuan Medical College, Nanchong, China PubMed articles Google scholar articles
Qibing Xie Department of Rheumatology and Immunology, West China Hospital of Sichuan University, Chengdu, China PubMed articles Google scholar articles
Cundong Mi Department of Rheumatology and Clinical Immunology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, China PubMed articles Google scholar articles
Lin Chen Department of Rheumatic Immunity, Jilin Province People's Hospital, Changchun, China PubMed articles Google scholar articles
Ning Zhang Rheumatology, Shengjing Hospital Affiliated to China Medical University, Shenyang, China PubMed articles Google scholar articles
Huiping Gong Department of Rheumatology and Clinical Immunology, Peace Hospital Affiliated to Changzhi Medical College, Changzhi, China PubMed articles Google scholar articles
Jing Zhu Department of Rheumatology and Immunology, Sichuan Provincial People's Hospital, Chengdu, China PubMed articles Google scholar articles
Yasong Li Department of Rheumatology and Clinical Immunology, Zhejiang Provincial People's Hospital, Hangzhou, China PubMed articles Google scholar articles
Hua Wei Rheumatology and Immunology Department, Northern Jiangsu People's Hospital, Yangzhou, China PubMed articles Google scholar articles
Long Qian Department of Rheumatology and Clinical Immunology, The Second Hospital of Anhui Medical University, Anhui, China PubMed articles Google scholar articles
Jian Wang Department of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Bengbu Medical College, Anhui, China PubMed articles Google scholar articles
Xiaofei Shi Department of Rheumatology and Clinical Immunology, The First Affiliated Hospital of Henan University of Science & Technology, Luoyang, China PubMed articles Google scholar articles
Hongtao Jin Department of Rheumatology and Immunology, The Second Hospital of Hebei Medical University, Shijiazhuang, China PubMed articles Google scholar articles
Zhenyu Jiang Department of Rheumatic Immunity, The First Hospital of Jilin University, Changchun, China PubMed articles Google scholar articles
Xi Xie Department of Clinical Immunology, The Second Xiangya Hospital of Central South University, Changsha, China PubMed articles Google scholar articles
Feng Zhan Department of Rheumatology and Immunology, Hainan General Hospital, Haikou, China PubMed articles Google scholar articles
Xiuqin Geng Department of Rheumatology and Immunology, Xinxiang Central Hospital, Xinxiang, China PubMed articles Google scholar articles
Zhaohui Zheng Department of Clinical Immunology, Xijing Hospital, the Fourth Military Medical University, Xi'an, China PubMed articles Google scholar articles
Zhengfu Du Department of Rheumatology and Immunology, Yuncheng Central Hospital, Yuncheng, China PubMed articles Google scholar articles
Guangchao Dong Clinical Research & Development, Jiangsu Hengrui Pharmaceuticals, Shanghai, China PubMed articles Google scholar articles
Yuqi Sun Biometric Department, Jiangsu Hengrui Pharmaceuticals, Shanghai, China PubMed articles Google scholar articles
Xiaofeng Zeng Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Beijing, China PubMed articles Google scholar articles

Correspondence to Dr Xiaofeng Zeng; zengxfpumc{at}163.com; xiaofeng.zeng{at}cstar.org.cn

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Citation

Liu J, Jiang Y, Zhang S, et al

Annals of the Rheumatic Diseases Published Online First: 27 November 2024. doi: 10.1136/ard-2024-226385

Publication history

Received July 8, 2024
Accepted November 4, 2024
First published November 27, 2024.

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